Certified Diabetes Educator Practice Exam 2025 - Free Practice Questions and Study Resource.

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What process involves the conversion of glycogen to glucose in the liver?

Glycogenesis

Glycogenolysis

The process that involves the conversion of glycogen to glucose in the liver is glycogenolysis. This is a crucial metabolic pathway where stored glycogen, primarily found in the liver and muscle tissues, is broken down into glucose molecules. This process is particularly important during periods of fasting or intense exercise, as it provides a quick source of glucose to maintain blood sugar levels and supply energy to cells, especially the brain and muscles.

In glycogenolysis, enzymes known as glycogen phosphorylase and debranching enzyme participate in breaking the alpha-1,4-glycosidic bonds between glucose units in the glycogen chain. The liberated glucose can then be utilized directly for energy or released into the bloodstream to regulate blood glucose levels.

The other processes mentioned serve different functions: glycogenesis is the synthesis of glycogen from glucose, gluconeogenesis is the creation of glucose from non-carbohydrate sources, and glycolysis is the breakdown of glucose for energy. Each of these pathways plays a distinct role in carbohydrate metabolism, emphasizing the importance of glycogenolysis in managing glucose supply from stored resources.

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Gluconeogenesis

Glycolysis

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