Certified Diabetes Educator Practice Exam 2025 - Free Practice Questions and Study Resource.

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Which sulfonylurea is typically preferred for elderly patients?

Glyburide

Glipizide

Glipizide is often considered the preferred sulfonylurea for elderly patients primarily due to its pharmacokinetic properties. It has a shorter duration of action and a lower risk of causing prolonged hypoglycemia compared to other sulfonylureas like Glyburide, which is associated with a longer half-life and increased risk of accumulation, particularly in patients with renal impairment common in older adults.

Elderly patients may also experience age-related changes in metabolism and kidney function, making medication management more complex. Glipizide's shorter duration allows for more flexibility in dosing and helps mitigate the chances of hypoglycemia, which can be more serious in this population. Its once-daily dosing option also promotes adherence and simplifies the medication regimen, further benefitting elderly patients.

That's why Glipizide is often the sulfonylurea of choice for managing diabetes in elderly individuals.

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Tolazamide

Chlorpropamide

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