Certified Diabetes Educator Practice Exam 2025 - Free Practice Questions and Study Resource.

In the postabsorptive state, which occurs several hours after eating when the nutrients from the food have been absorbed and blood glucose levels begin to decline, there is a physiological shift in hormone levels. During this phase, the body starts to rely on stored energy substrates to maintain blood glucose levels, leading to a decrease in plasma insulin levels.

Insulin is a hormone that facilitates glucose uptake into cells and promotes storage of nutrients, so after the immediate effects of food consumption have passed, insulin secretion decreases. This reduction is important as it allows other hormones like glucagon to increase and stimulate the release of glucose from the liver, ensuring that blood glucose levels are maintained for energy.

In contrast to this, plasma levels of glucagon and other counter-regulatory hormones typically rise to keep blood sugar levels stable during the postabsorptive state. Thus, the correct understanding of this physiological transition emphasizes the role of decreasing insulin levels as the body shifts to mobilizing energy stores.