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What does intermittent claudication refer to?

Pain in the upper extremities

Pain in the lower extremities during physical activity

Intermittent claudication refers specifically to pain or discomfort that occurs in the lower extremities—typically the legs—during physical activities such as walking or climbing stairs. This pain arises due to inadequate blood flow to the muscles, which is often a sign of peripheral artery disease. When the muscles in the legs do not receive enough oxygen-rich blood, they become painful during exertion. This pain typically resolves with rest, as blood flow is restored and oxygen supply increases.

Additionally, while other options mention various types of pain or physiological responses, none accurately describe the specific clinical phenomenon associated with intermittent claudication. Pain in the upper extremities or persistent muscle soreness does not relate to the vascular insufficiency seen in claudication. Sudden increases in blood pressure are distinct cardiovascular events unrelated to the muscle pain experienced during exertive activities. Thus, the answer emphasizing the pain in the lower extremities during physical activity captures the true essence of intermittent claudication accurately.

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A sudden increase in blood pressure

Persistent muscle soreness

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