Certified Diabetes Educator Practice Exam 2025 - Free Practice Questions and Study Resource.

Thiazolidinediones (TZDs) are a class of medications used to treat type 2 diabetes by improving insulin sensitivity in muscle and adipose tissue and reducing hepatic glucose production. The correct answer identifies pioglitazone and rosiglitazone as members of this class, both of which are effective for managing blood glucose levels in individuals with diabetes.

Pioglitazone and rosiglitazone work by activating peroxisome proliferator-activated receptors (PPARs), which play a crucial role in glucose and lipid metabolism. By increasing insulin sensitivity, these medications help lower blood sugar levels and have a beneficial effect on lipid profiles.

The other choices consist of medications that belong to different classes. Acarbose is an alpha-glucosidase inhibitor, which slows carbohydrate absorption in the intestines, while sitagliptin belongs to the DPP-4 inhibitors class that increases incretin levels to stimulate insulin release. Glyburide is a sulfonylurea that increases insulin secretion from the pancreas, and metformin is a biguanide that primarily decreases hepatic glucose production. Lastly, exenatide and liraglutide are GLP-1 receptor agonists that enhance insulin secretion in a glucose