Certified Diabetes Educator Practice Exam 2025 - Free Practice Questions and Study Resource.

Fructose has been shown to raise triglyceride levels, which is a significant concern regarding its use as a sweetener. Consumption of high amounts of fructose, particularly in the form of sweeteners like high-fructose corn syrup, can lead to metabolic disturbances. When fructose is metabolized, it is primarily processed in the liver where it can promote de novo lipogenesis, the process of converting excess sugars into fatty acids. This increase in fatty acid production can subsequently elevate triglyceride levels in the bloodstream.

Elevated triglycerides are a risk factor for cardiovascular disease and can contribute to the development of insulin resistance and fatty liver disease. Therefore, the connection between fructose consumption and increased triglyceride levels highlights the need for caution in its use as a sweetener, especially for individuals who are already at risk for metabolic syndrome or cardiovascular issues.

The other effects associated with fructose consumption, such as potential impacts on HDL and LDL cholesterol levels, as well as blood pressure, are less directly related to its primary metabolic pathways compared to triglyceride elevation. Hence, the concern surrounding fructose as a sweetener is primarily linked to its effect on raising triglyceride levels.