Certified Diabetes Educator Practice Exam 2025 - Free Practice Questions and Study Resource.

Repaglinide is an excellent choice for targeting postprandial blood glucose levels due to its mechanism of action. It belongs to the class of medications known as meglitinides, which stimulate the pancreas to release insulin in reaction to meals. This fast-acting insulin secretagogue is particularly effective because it helps lower blood glucose levels that rise after eating.

Repaglinide is taken shortly before meals, allowing it to effectively address spikes in glucose that occur after food intake. The onset of action is quick, leading to increased insulin secretion in response to food consumption, making it specifically beneficial for controlling postprandial hyperglycemia.

In contrast, other medications listed work differently. Metformin primarily decreases hepatic glucose production and increases insulin sensitivity, but it does not specifically address postprandial spikes. Sitagliptin, a DPP-4 inhibitor, enhances incretin hormones to reduce glucose levels but has a more prolonged action that does not target postprandial peaks as effectively. Liraglutide, a GLP-1 receptor agonist, helps control blood glucose and promotes weight loss but typically has a longer-lasting effect that is not as focused on immediate post-meal blood glucose control.

Thus, repaglinide stands