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Omega-3 fatty acids are recognized for their overall heart health benefits, including anti-inflammatory properties and the potential to raise HDL (high-density lipoprotein) cholesterol levels. However, research indicates that while omega-3 fatty acids may contribute to cardiovascular health, their direct effect on lowering LDL (low-density lipoprotein) cholesterol—the "bad" cholesterol associated with increased heart disease risks—is not as pronounced compared to other lifestyle strategies.

In contrast, regular exercise is well-established as an effective method for improving cholesterol profiles, including lowering LDL levels. Increased fiber intake, particularly soluble fiber, has been shown to effectively bind cholesterol in the digestive system and contribute to its excretion, thus reducing LDL cholesterol levels. Likewise, reducing saturated fat consumption directly impacts cholesterol levels by decreasing the amount of LDL cholesterol synthesized in the liver.

While incorporating omega-3 fatty acids into the diet is beneficial for heart health, it is the least effective strategy among the given options specifically for lowering LDL cholesterol.